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Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE(2)-dependent mechanism

Mesenchymal stem cells (MSCs) are speculated to act at macrophage-injury interfaces to mediate efficient repair. To explore this facet in-depth this study evaluates the influence of MSCs on human macrophages existing in distinct functional states. MSCs promoted macrophage differentiation, enhanced r...

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Pubblicato in:Sci Rep
Autori principali: Vasandan, Anoop Babu, Jahnavi, Sowmya, Shashank, Chandanala, Prasad, Priya, Kumar, Anujith, Prasanna, S. Jyothi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133610/
https://ncbi.nlm.nih.gov/pubmed/27910911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38308
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