PGC-1α dictates endothelial function through regulation of eNOS expression

Endothelial dysfunction is a characteristic of many vascular related diseases such as hypertension. Peroxisome proliferator activated receptor gamma, coactivator 1α (PGC-1α) is a unique stress sensor that largely acts to promote adaptive responses. Therefore, we sought to define the role of endothel...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Craige, Siobhan M., Kröller-Schön, Swenja, Li, Chunying, Kant, Shashi, Cai, Shenghe, Chen, Kai, Contractor, Mayur M., Pei, Yongmei, Schulz, Eberhard, Keaney, John F.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133545/
https://ncbi.nlm.nih.gov/pubmed/27910955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38210
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