CR1 exon variants are associated with lowered CR1 expression and increased susceptibility to SLE in a Plasmodium falciparum endemic population

BACKGROUND: Complement receptor 1 (CR1) plays an important role in immune complex clearance by opsonisation and possibly protects subjects from development of autoantibodies. Lower CR1 expression has been associated with susceptibility to systemic lupus erythematosus (SLE). In contrast, subjects dis...

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Bibliographische Detailangaben
Veröffentlicht in:Lupus Sci Med
Hauptverfasser: Panda, Aditya K, Ravindran, Balachandran, Das, Bidyut K
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2016
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133404/
https://ncbi.nlm.nih.gov/pubmed/27933195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2016-000145
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