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Positive selection of candidate tumor-suppressor genes by subtractive hybridization.

A positive selection system designed to identify and recover candidate tumor-suppressor genes is described. The system compares mRNA expression of genes from normal and tumor-derived human mammary epithelial cells grown in a special medium that supports similar growth rates of the two cell types. mR...

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Detalhes bibliográficos
Main Authors: Lee, S W, Tomasetto, C, Sager, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51332/
https://ncbi.nlm.nih.gov/pubmed/1849277
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