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Study of ethanol-induced Golgi disorganization reveals the potential mechanism of alcohol-impaired N-glycosylation

BACKGROUND: It is known that ethanol (EtOH) and its metabolites have a negative effect on protein glycosylation. The fragmentation of the Golgi apparatus induced by alteration of the structure of largest Golgi matrix protein, giantin, is the major consequence of damaging effects of EtOH-metabolism o...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Casey, Carol A., Bhat, Ganapati, Holzapfel, Melissa S., Petrosyan, Armen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133184/
https://ncbi.nlm.nih.gov/pubmed/27748959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13247
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