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Fecal metabolomics in pediatric spondyloarthritis implicate decreased metabolic diversity and altered tryptophan metabolism as pathogenic factors

OBJECTIVE: We have previously shown alterations in the composition of the gut microbiota in children with enthesitis-related arthritis (ERA). To explore the mechanisms by which an altered microbiota might predispose to arthritis, we performed metabolomic profiling of fecal samples of children with E...

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Publicat a:Genes Immun
Autors principals: Stoll, Matthew L, Kumar, Ranjit, Lefkowitz, Elliot, Cron, Randy Q, Morrow, Casey D, Barnes, Stephen
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133160/
https://ncbi.nlm.nih.gov/pubmed/27786174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.38
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