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Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2

We recently found that the product of the AES gene functions as a metastasis suppressor of colorectal cancer (CRC) in both humans and mice. Expression of amino‐terminal enhancer of split (AES) protein is significantly decreased in liver metastatic lesions compared with primary colon tumors. To inves...

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Publicat a:Cancer Sci
Autors principals: Kakizaki, Fumihiko, Sonoshita, Masahiro, Miyoshi, Hiroyuki, Itatani, Yoshiro, Ito, Shinji, Kawada, Kenji, Sakai, Yoshiharu, Taketo, M. Mark
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132282/
https://ncbi.nlm.nih.gov/pubmed/27561171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13063
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