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Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2

We recently found that the product of the AES gene functions as a metastasis suppressor of colorectal cancer (CRC) in both humans and mice. Expression of amino‐terminal enhancer of split (AES) protein is significantly decreased in liver metastatic lesions compared with primary colon tumors. To inves...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kakizaki, Fumihiko, Sonoshita, Masahiro, Miyoshi, Hiroyuki, Itatani, Yoshiro, Ito, Shinji, Kawada, Kenji, Sakai, Yoshiharu, Taketo, M. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132282/
https://ncbi.nlm.nih.gov/pubmed/27561171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13063
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