In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia

BACKGROUND: Approximately fifty percent of patients with acute myeloid leukemia can be cured with current therapeutic strategies which include, standard dose chemotherapy for patients at standard risk of relapse as assessed by cytogenetic and molecular analysis, or high-dose chemotherapy with alloge...

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Pubblicato in:PLoS One
Autori principali: Minagawa, Kentaro, Jamil, Muhammad O., AL-Obaidi, Mustafa, Pereboeva, Larisa, Salzman, Donna, Erba, Harry P., Lamb, Lawrence S., Bhatia, Ravi, Mineishi, Shin, Di Stasi, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132227/
https://ncbi.nlm.nih.gov/pubmed/27907031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166891
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