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Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study

BACKGROUND: Despite significant advances in quantitative neuroimaging, the diagnosis of ALS remains clinical and MRI-based biomarkers are not currently used to aid the diagnosis. The objective of this study is to develop a robust, disease-specific, multimodal classification protocol and validate its...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schuster, Christina, Hardiman, Orla, Bede, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132189/
https://ncbi.nlm.nih.gov/pubmed/27907080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167331
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