Silver Nanoparticle-Directed Mast Cell Degranulation Is Mediated through Calcium and PI3K Signaling Independent of the High Affinity IgE Receptor

Engineered nanomaterial (ENM)-mediated toxicity often involves triggering immune responses. Mast cells can regulate both innate and adaptive immune responses and are key effectors in allergic diseases and inflammation. Silver nanoparticles (AgNPs) are one of the most prevalent nanomaterials used in...

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Bibliographic Details
Published in:PLoS One
Main Authors: Alsaleh, Nasser B., Persaud, Indushekhar, Brown, Jared M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131952/
https://ncbi.nlm.nih.gov/pubmed/27907088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167366
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