Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging

The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely truncated sensory cilia of hypomorphic IFT mutants i...

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Cornils, Astrid, Maurya, Ashish K., Tereshko, Lauren, Kennedy, Julie, Brear, Andrea G., Prahlad, Veena, Blacque, Oliver E., Sengupta, Piali
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131903/
https://ncbi.nlm.nih.gov/pubmed/27906968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006325
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