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Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2
DOCK8 deficiency is an autosomal recessive combined immunodeficiency disease associated with elevated IgE, atopy, recurrent sinopulmonary and cutaneous viral infections, and malignancy. The DOCK8 protein is critical for cytoskeletal organization, and deficiency impairs dendritic cell transmigration,...
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| Published in: | Dermatol Clin |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131797/ https://ncbi.nlm.nih.gov/pubmed/27890234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.det.2016.07.002 |
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