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Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2

DOCK8 deficiency is an autosomal recessive combined immunodeficiency disease associated with elevated IgE, atopy, recurrent sinopulmonary and cutaneous viral infections, and malignancy. The DOCK8 protein is critical for cytoskeletal organization, and deficiency impairs dendritic cell transmigration,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dermatol Clin
Prif Awduron: Dimitrova, Dimana, Freeman, Alexandra F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131797/
https://ncbi.nlm.nih.gov/pubmed/27890234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.det.2016.07.002
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