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Approved Glycopeptide Antibacterial Drugs: Mechanism of Action and Resistance

The glycopeptide antimicrobials are a group of natural product and semisynthetic glycosylated peptides that show antibacterial activity against Gram-positive organisms through inhibition of cell-wall synthesis. This is achieved primarily through binding to the d-alanyl-d-alanine terminus of the lipi...

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Publicado en:Cold Spring Harb Perspect Med
Main Authors: Zeng, Daina, Debabov, Dmitri, Hartsell, Theresa L., Cano, Raul J., Adams, Stacy, Schuyler, Jessica A., McMillan, Ronald, Pace, John L.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131748/
https://ncbi.nlm.nih.gov/pubmed/27663982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026989
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