Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques

OBJECTIVE: Resting CD4(+) T cells have been recognized as the major cell reservoir of latent HIV-1 during antiretroviral therapy (ART). Using an simian immunodeficiency virus (SIV)/macaque model for AIDS and HIV-related neurocognitive disorders we assessed the contribution of the brain to viral late...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Gama, Lucio, Abreu, Celina M., Shirk, Erin N., Price, Sarah L., Li, Ming, Laird, Greg M., Pate, Kelly A. Metcalf, Wietgrefe, Stephen W., O’Connor, Shelby L., Pianowski, Luiz, Haase, Ashley T., Van Lint, Carine, Siliciano, Robert F., Clements, Janice E.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131686/
https://ncbi.nlm.nih.gov/pubmed/27898590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001267
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