Sodium ascorbate kills Candida albicans in vitro via iron-catalyzed Fenton reaction: importance of oxygenation and metabolism

AIM: Ascorbate can inhibit growth and even decrease viability of various microbial species including Candida albicans. However the optimum conditions and the mechanism of action are unclear. MATERIALS/METHODOLOGY: Candida albicans shaken for 90 min in a buffered solution of ascorbate (90 mM) gave a...

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Detalhes bibliográficos
Publicado no:Future Microbiol
Main Authors: Avci, Pinar, Freire, Fernanda, Banvolgyi, Andras, Mylonakis, Eleftherios, Wikonkal, Norbert M, Hamblin, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131655/
https://ncbi.nlm.nih.gov/pubmed/27855492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb-2016-0063
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