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Protection from lethal herpes simplex virus type 1 infection by vaccination with a UL41-deficient recombinant strain
The UL41 gene of herpes simplex virus type 1 (HSV-1) encodes a virion host shut off protein which is involved in immune evasion. The growth and virulence of HSV-1 is markedly reduced by the deletion of UL41. In this report, the UL41-deleted recombinant HSV-1 strain VR∆41 was evaluated as a prophylac...
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| Udgivet i: | Fukushima J Med Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Fukushima Society of Medical Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131579/ https://ncbi.nlm.nih.gov/pubmed/26983589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5387/fms.2015-24 |
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