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Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation

The pathogenesis of pain in lumbar disc herniation (LDH) remains poorly understood. We have recently demonstrated that voltage-gated sodium channels (VGSCs) in dorsal root ganglion (DRG) neurons were sensitized in a rat model of LDH. However, the detailed molecular mechanism for sensitization of VGS...

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מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Yan, Jun, Hu, Shufen, Zou, Kang, Xu, Min, Wang, Qianliang, Miao, Xiuhua, Yu, Shan Ping, Xu, Guang-Yin
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131276/
https://ncbi.nlm.nih.gov/pubmed/27905525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38188
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