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Protective Efficacy of a Novel Alpha Hemolysin Subunit Vaccine (AT62) against Staphylococcus aureus Skin and Soft Tissue Infections

Alpha hemolysin (Hla) is a pore-forming toxin produced by most Staphylococcus aureus isolates. Hla is reported to play a key role in the pathogenesis of staphylococcal infections, such as skin and soft tissue infection, pneumonia, and lethal peritonitis. This study makes use of a novel recombinant s...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Adhikari, Rajan P., Thompson, Christopher D., Aman, M. Javad, Lee, Jean C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130608/
https://ncbi.nlm.nih.gov/pubmed/27847174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.09.061
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