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Changes in cardiac Na(v)1.5 expression, function, and acetylation by pan-histone deacetylase inhibitors
Histone deacetylase (HDAC) inhibitors are small molecule anticancer therapeutics that exhibit limiting cardiotoxicities including QT interval prolongation and life-threatening cardiac arrhythmias. Because the molecular mechanisms for HDAC inhibitor-induced cardiotoxicity are poorly understood, we pe...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5130491/ https://ncbi.nlm.nih.gov/pubmed/27638876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00156.2016 |
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