Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype

Non-muscle invasive (superficial) bladder cancer is a low-grade malignancy with good prognosis, while muscle invasive (invasive) bladder cancer is a high-grade malignancy with poor prognosis. N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) induces superficial bladder cancers with papillary morphology in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kanemoto, Kazuhiro, Fukuta, Katsuhiro, Kawai, Noriyasu, Tozawa, Keiichi, Ochiai, Masako, Okamoto, Koji, Ohnami, Sumiko, Sakamoto, Hiromi, Yoshida, Teruhiko, Kanai, Yae, Katoh, Masaru, Yasui, Takahiro, Kohri, Kenjiro, Kakizoe, Tadao, Nakagama, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130269/
https://ncbi.nlm.nih.gov/pubmed/27902773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167374
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