Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling

Piceatannol, a resveratrol metabolite, is a phenolic compound found in red wine and grapes. We investigated the effect of piceatannol on renal fibrosis and histone deacetylase (HDAC) expression in a mouse model of unilateral ureteral obstruction (UUO). Fibrosis was established by UUO and piceatannol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choi, Sin Young, Piao, Zhe Hao, Jin, Li, Kim, Jung Ha, Kim, Gwi Ran, Ryu, Yuhee, Lin, Ming Quan, Kim, Hyung-Seok, Kee, Hae Jin, Jeong, Myung Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130266/
https://ncbi.nlm.nih.gov/pubmed/27902771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167340
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