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Synaptic microRNAs Coordinately Regulate Synaptic mRNAs: Perturbation by Chronic Alcohol Consumption

Local translation of mRNAs in the synapse has a major role in synaptic structure and function. Chronic alcohol use causes persistent changes in synaptic mRNA expression, possibly mediated by microRNAs localized in the synapse. We profiled the transcriptome of synaptoneurosomes (SN) obtained from the...

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Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Most, Dana, Leiter, Courtney, Blednov, Yuri A, Harris, R Adron, Mayfield, R Dayne
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130129/
https://ncbi.nlm.nih.gov/pubmed/26105134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.179
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