Single-Nucleotide Polymorphism of the FKBP5 Gene and Childhood Maltreatment as Predictors of Structural Changes in Brain Areas Involved in Emotional Processing in Depression

The gene expressing the FK506 binding protein 51 (FKBP5) is involved in the regulation of glucocorticoid receptor sensitivity. The rs1360780 SNP in this gene (T allele vs C homozygous) has been found to be associated with major depressive disorder (MDD). The aim of our study was to investigate wheth...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Tozzi, Leonardo, Carballedo, Angela, Wetterling, Friedrich, McCarthy, Hazel, O'Keane, Veronica, Gill, Michael, Morris, Derrek, Fahey, Ciara, Meaney, James, Frodl, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130124/
https://ncbi.nlm.nih.gov/pubmed/26076833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.170
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