A herpesvirus protein selectively inhibits cellular mRNA nuclear export

Nuclear mRNA export is highly regulated to ensure accurate cellular gene expression. Viral inhibition of cellular mRNA export can enhance viral access to the cellular translation machinery and prevent anti-viral protein production but is generally thought to be nonselective. We report that ORF10 of...

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Pubblicato in:Cell Host Microbe
Autori principali: Gong, Danyang, Kim, Yong Hoon, Xiao, Yuchen, Du, Yushen, Xie, Yafang, Lee, Kevin K., Feng, Jun, Farhat, Nisar, Zhao, Dawei, Shu, Sara, Dai, Xinghong, Chanda, Sumit K., Rana, Tariq M., Krogan, Nevan J., Sun, Ren, Wu, Ting-Ting
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130111/
https://ncbi.nlm.nih.gov/pubmed/27832591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.004
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