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Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing

BACKGROUND: Detection of circulating cell-free DNA (cfDNA) has potential clinical value for assessing tumor biology in patients with hepatocellular carcinoma (HCC), yet many traditional assays lack robustness. This study was the first to apply a high-throughput sequencing platform to detect tumor-as...

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發表在:	Oncotarget
Main Authors:	Liao, Wenjun, Yang, Huayu, Xu, Haifeng, Wang, Yanan, Ge, Penglei, Ren, Jinjun, Xu, Wei, Lu, Xin, Sang, Xinting, Zhong, Shouxian, Zhang, Hongbing, Mao, Yilei
格式:	Artigo
語言:	Inglês
出版:	Impact Journals LLC 2016
主題:	Research Paper
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5130021/ https://ncbi.nlm.nih.gov/pubmed/27248174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9629
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Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing

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