Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity

Binding of leukemia cells to the bone marrow extracellular matrix (ECM) through integrins might influence drug response and the survival of acute myeloid leukemia (AML). However, the functions of integrin in AML are needed to be clarified. Data from The Cancer Genome Atlas (TCGA) were retrieved and...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Yi, Hai, Zeng, Dongfeng, Shen, Zhaohua, Liao, Jun, Wang, Xiaoguo, Liu, Yao, Zhang, Xi, Kong, Peiyan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130015/
https://ncbi.nlm.nih.gov/pubmed/27248172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9617
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