Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity

Binding of leukemia cells to the bone marrow extracellular matrix (ECM) through integrins might influence drug response and the survival of acute myeloid leukemia (AML). However, the functions of integrin in AML are needed to be clarified. Data from The Cancer Genome Atlas (TCGA) were retrieved and...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yi, Hai, Zeng, Dongfeng, Shen, Zhaohua, Liao, Jun, Wang, Xiaoguo, Liu, Yao, Zhang, Xi, Kong, Peiyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130015/
https://ncbi.nlm.nih.gov/pubmed/27248172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9617
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