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Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer

Defining biomarkers that predict therapeutic effects and adverse events is a crucial mandate to guide patient selection for personalized cancer treatments. In the present study, we applied a pharmacometabolomics approach to identify biomarkers potentially associated with pathological complete respon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Miolo, Gianmaria, Muraro, Elena, Caruso, Donatella, Crivellari, Diana, Ash, Anthony, Scalone, Simona, Lombardi, Davide, Rizzolio, Flavio, Giordano, Antonio, Corona, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129972/
https://ncbi.nlm.nih.gov/pubmed/27223427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9489
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