Down-regulation of microRNA-320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF-1

Insulin-like growth factor-1 (IGF-1) is an important regulator of cardiomyocyte homeostasis and cardiac structure, and the prosurvival and antiapoptotic effects of IGF-1 have been investigated. However, the effect of microRNA-320 (miR-320) in ischemia and reperfusion (I/R) by targeting IGF-1 is rare...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Song, Chun-Li, Liu, Bin, Diao, Hong-Ying, Shi, Yong-Feng, Zhang, Ji-Chang, Li, Yang-Xue, Liu, Ning, Yu, Yun-Peng, Wang, Guan, Wang, Jin-Peng, Li, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129967/
https://ncbi.nlm.nih.gov/pubmed/27175593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9240
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