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The superior regenerative potential of muscle-derived stem cells for articular cartilage repair is attributed to high cell survival and chondrogenic potential

Three populations of muscle-derived cells (PP1, PP3, and PP6) were isolated from mouse skeletal muscle using modified preplate technique and retrovirally transduced with BMP4/GFP.  In vitro, the PP1 cells (fibroblasts) proliferated significantly slower than the PP3 (myoblasts) and PP6 cells (muscle-...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Li, Hongshuai, Lu, Aiping, Tang, Ying, Beckman, Sarah, Nakayama, Naoki, Poddar, Minakshi, Hogan, MaCalus V, Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129874/
https://ncbi.nlm.nih.gov/pubmed/27990446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.65
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