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Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertension

Hyperhomocysteinemia (HHcy) has been observed to promote hypertension, but the mechanisms are unclear. Toll-like receptor 4 (TLR-4) is a cellular membrane protein that is ubiquitously expressed in all cell types of the vasculature. TLR-4 activation has been known to promote inflammation that has bee...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Familtseva, Anastasia, Chaturvedi, Pankaj, Kalani, Anuradha, Jeremic, Nevena, Metreveli, Naira, Kunkel, George H., Tyagi, Suresh C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129755/
https://ncbi.nlm.nih.gov/pubmed/27488663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00088.2016
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