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Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats

BACKGROUND: Our recent findings support the idea that 3-deoxyglucosone (3DG), a dietary composition, has been suggested as an independent factor for the development of prediabetes. Secretion of glucagon-like peptide-1 (GLP-1) has been suggested to be impaired in T2DM and in conditions associated wit...

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Pubblicato in:Diabetol Metab Syndr
Autori principali: Zhang, Lurong, Song, Xiudao, Zhou, Liang, Liang, Guoqiang, Xu, Heng, Wang, Fei, Huang, Fei, Jiang, Guorong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129672/
https://ncbi.nlm.nih.gov/pubmed/27956941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-016-0194-9
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