Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth

Mycobacterium avium complex induces macrophage apoptosis. However, the M. avium components that inhibit or trigger apoptosis and their regulating mechanisms remain unclear. We recently identified the immunodominant MAV2054 protein by fractionating M. avium culture filtrate protein by multistep chrom...

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Udgivet i:Sci Rep
Main Authors: Lee, Kang-In, Whang, Jake, Choi, Han-Gyu, Son, Yeo-Jin, Jeon, Haet Sal, Back, Yong Woo, Park, Hye-Soo, Paik, Seungwha, Park, Jeong-Kyu, Choi, Chul Hee, Kim, Hwa-Jung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129020/
https://ncbi.nlm.nih.gov/pubmed/27901051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37804
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