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Membrane Core-Specific Antimicrobial Action of Cathelicidin LL-37 Peptide Switches Between Pore and Nanofibre Formation

Membrane-disrupting antimicrobial peptides provide broad-spectrum defence against localized bacterial invasion in a range of hosts including humans. The most generally held consensus is that targeting to pathogens is based on interactions with the head groups of membrane lipids. Here we show that th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shahmiri, Mahdi, Enciso, Marta, Adda, Christopher G., Smith, Brian J., Perugini, Matthew A., Mechler, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128859/
https://ncbi.nlm.nih.gov/pubmed/27901075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38184
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