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Chiral Alkyl Halides: Underexplored Motifs in Medicine

While alkyl halides are valuable intermediates in synthetic organic chemistry, their use as bioactive motifs in drug discovery and medicinal chemistry is rare in comparison. This is likely attributable to the common misconception that these compounds are merely non-specific alkylators in biological...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Gál, Bálint, Bucher, Cyril, Burns, Noah Z.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128749/
https://ncbi.nlm.nih.gov/pubmed/27827902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14110206
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