Network analysis of human post-mortem microarrays reveals novel genes, microRNAs, and mechanistic scenarios of potential importance in fighting huntington's disease

Huntington's disease is a progressive neurodegenerative disorder characterized by motor disturbances, cognitive decline, and neuropsychiatric symptoms. In this study, we utilized network-based analysis in an attempt to explore and understand the underlying molecular mechanism and to identify cr...

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Bibliographic Details
Published in:Comput Struct Biotechnol J
Main Authors: Chandrasekaran, Sreedevi, Bonchev, Danail
Format: Artigo
Language:Inglês
Published: Research Network of Computational and Structural Biotechnology 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128196/
https://ncbi.nlm.nih.gov/pubmed/27924190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.02.001
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