Epstein-Barr Virus Latent Membrane Protein 2A (LMP2A) Enhances IL-10 production through the Activation of Bruton’s Tyrosine Kinase and STAT3

Previous data demonstrate that Epstein-Barr Virus Latent Membrane Protein 2A (LMP2A) enhances IL-10 to promote the survival of LMP2A-expressing B cell lymphomas. Since STAT3 is an important regulator of IL-10 production, we hypothesized that LMP2A activates a signal transduction cascade that increas...

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Détails bibliographiques
Publié dans:Virology
Auteurs principaux: Incrocci, Ryan, Barse, Levi, Stone, Amanda, Vagvala, Sai, Montesano, Michael, Subramaniam, Vijay, Swanson-Mungerson, Michelle
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127766/
https://ncbi.nlm.nih.gov/pubmed/27792904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.10.015
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