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The Endocytic Pathway in Microglia During Health, Aging and Alzheimer’s Disease

Microglia, the main phagocytes of the central nervous system (CNS), are involved in the surveillance and maintenance of nervous tissue. During normal tissue homeostasis, microglia migrate within the CNS, phagocytose dead cells and tissue debris, and modulate synapse pruning and spine formation via c...

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Detalhes bibliográficos
Publicado no:Ageing Res Rev
Main Authors: Solé-Domènech, Santiago, Cruz, Dana L., Capetillo-Zarate, Estibaliz, Maxfield, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127718/
https://ncbi.nlm.nih.gov/pubmed/27421577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.07.002
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