Scientific and political challenges in North America’s first randomized controlled trial of heroin-assisted treatment for severe heroin addiction: Rationale and design of the NAOMI study

BACKGROUND: Heroin addiction is a chronic relapsing disease, best treated with opioid-agonist substitution therapy such as methadone maintenance. However, a subset of the most severely affected individuals do not benefit sufficiently from this treatment. The North American Opiate Medication Initiati...

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Published in:Clin Trials
Main Authors: Oviedo-Joekes, Eugenia, Nosyk, Bohdan, Marsh, David C, Guh, Daphne, Brissette, Suzanne, Gartry, Candice, Krausz, Michael, Anis, Aslam, Schechter, Martin T
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127700/
https://ncbi.nlm.nih.gov/pubmed/19528135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774509105222
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