Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia

Preeclampsia (PE) complicates ∼5% of human pregnancies and is one of the leading causes of pregnancy-related maternal deaths. The only definitive treatment, induced delivery, invariably results in prematurity, and in severe early-onset cases may lead to fetal death. Many currently available antihype...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Li, Feng, Fushima, Tomofumi, Oyanagi, Gen, Townley-Tilson, H. W. Davin, Sato, Emiko, Nakada, Hironobu, Oe, Yuji, Hagaman, John R., Wilder, Jennifer, Li, Manyu, Sekimoto, Akiyo, Saigusa, Daisuke, Sato, Hiroshi, Ito, Sadayoshi, Jennette, J. Charles, Maeda, Nobuyo, Karumanchi, S. Ananth, Smithies, Oliver, Takahashi, Nobuyuki
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127378/
https://ncbi.nlm.nih.gov/pubmed/27821757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614947113
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