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Spatiotemporal dynamics of androgen signaling underlie sexual differentiation and congenital malformations of the urethra and vagina

Disorders of sex development (DSDs) are congenital anomalies that affect sexual differentiation of genitourinary organs and secondary sex characters. A common cause of female genital virilization is congenital adrenal hyperplasia (CAH), in which excess androgen production during development of 46XX...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Larkins, Christine E., Enriquez, Ana B., Cohn, Martin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127369/
https://ncbi.nlm.nih.gov/pubmed/27821748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610471113
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