Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes

Diabetic bladder dysfunction (DBD) is a common urological complication of diabetes. Innate immune system activation via Toll-like receptor 4 (TLR4) leads to inflammation and oxidative stress and was implicated in diabetes pathophysiology. We hypothesized that bladder hypertrophy and hypercontractili...

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Bibliographic Details
Published in:Diabetes
Main Authors: Szasz, Theodora, Wenceslau, Camilla F., Burgess, Beth, Nunes, Kenia P., Webb, R. Clinton
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2016
Subjects:
Complications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127246/
https://ncbi.nlm.nih.gov/pubmed/27650857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0480
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