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Leptin augments coronary vasoconstriction and smooth muscle proliferation via a Rho kinase dependent pathway

Leptin has been implicated as a key upstream mediator of pathways associated with coronary vascular dysfunction and disease. The purpose of this investigation was to test the hypothesis that leptin modifies the coronary artery proteome and promotes increases in coronary smooth muscle contraction and...

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Publicat a:Basic Res Cardiol
Autors principals: Noblet, Jillian N., Goodwill, Adam G., Sassoon, Daniel J., Kiel, Alexander M., Tune, Johnathan D.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126981/
https://ncbi.nlm.nih.gov/pubmed/26975316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0545-6
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