Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching

BACKGROUND/OBJECTIVES: Obesity-induced steatohepatitis accompanied by activated hepatic macrophages/Kupffer cells facilitates the progression of hepatic fibrinogenesis and exacerbates metabolic derangements such as insulin resistance. Heme oxyganase-1 (HO-1) modulates tissue macrophage phenotypes an...

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Veröffentlicht in:Nutr Res Pract
Hauptverfasser: Kim, Chu-Sook, Choi, Hye-Seon, Joe, Yeonsoo, Chung, Hun Taeg, Yu, Rina
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Nutrition Society and the Korean Society of Community Nutrition 2016
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126412/
https://ncbi.nlm.nih.gov/pubmed/27909560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4162/nrp.2016.10.6.623
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