SIRT6 suppresses mitochondrial defects and cell death via the NF-κB pathway in myocardial hypoxia/reoxygenation induced injury

The present study explored changes of the SIRT6/NF-κB pathway in myocardial hypoxia/reoxygenation induced injury and the effects on mitochondrial damage and myocardial damage by regulating SIRT6. SIRT6 expression decreased and NF-κB expression increased in H9c2 cells during hypoxic injury. Cell deat...

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Vydáno v:Am J Transl Res
Hlavní autoři: Cheng, Ming-Yue, Cheng, You-Wei, Yan, Jun, Hu, Xiao-Qin, Zhang, Hui, Wang, Zhi-Rong, Yin, Qin, Cheng, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126343/
https://ncbi.nlm.nih.gov/pubmed/27904701
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