Berberine upregulates miR-22-3p to suppress hepatocellular carcinoma cell proliferation by targeting Sp1

MicroRNA-22-3p (miR-22-3p) is downregulated in hepatocellular carcinoma (HCC), which contributes to the development and progression of HCC. In this study, berberine treatment upregulated miR-22-3p expression in HepG2 cells. Therefore, we investigated whether berberine suppresses the proliferation of...

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Publicat a:Am J Transl Res
Autors principals: Chen, Jie, Wu, Fei-Xiang, Luo, Hong-Lin, Liu, Jun-Jie, Luo, Tao, Bai, Tao, Li, Le-Qun, Fan, Xiao-Hui
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126335/
https://ncbi.nlm.nih.gov/pubmed/27904693
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