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Rapamycin targets Interleukin 6 (IL-6) expression and suppresses endothelial cell invasion stimulated by tumor cells

mTOR inhibitors have potent antiangiogenic and anti-lymphangiogenic effects in addition to their growth inhibitory effects in head and neck squamous cell carcinoma (HNSCC). Lymphatogenous spread is much more predominant in HNSCC than hematogenous spread and significantly decreases survival. In this...

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Библиографические подробности
Опубликовано в: :Am J Transl Res
Главные авторы: Ekshyyan, Oleksandr, Khandelwal, Alok R, Rong, Xiaohua, Moore-Medlin, Tara, Ma, Xiaohui, Alexander, Jonathan Steven, Nathan, Cherie-Ann O
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126325/
https://ncbi.nlm.nih.gov/pubmed/27904683
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