An engineered FGF21 variant, LY2405319, can prevent non-alcoholic steatohepatitis by enhancing hepatic mitochondrial function

Non-alcoholic fatty liver disease (NAFLD) is a prevalent obesity-related disease that affects large populations throughout the world due to excessive calorie intake and an increasingly sedentary lifestyle. Fibroblast growth factor 21 (FGF21) has recently emerged as a promising therapeutic candidate...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Lee, Ju Hee, Kang, Yea Eun, Chang, Joon Young, Park, Ki Cheol, Kim, Hyeon-Woo, Kim, Jung Tae, Kim, Hyun Jin, Yi, Hyon-Seung, Shong, Minho, Chung, Hyo Kyun, Kim, Koon Soon
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126319/
https://ncbi.nlm.nih.gov/pubmed/27904677
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