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VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts

ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family is known to play an important role in the pathogenesis of osteoarthritis (OA), working on aggrecan degradation or altering the integrity of extracellular matrix (ECM). Thus, the main purpose of our study was to define the...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Pérez‐García, Selene, Carrión, Mar, Gutiérrez‐Cañas, Irene, González‐Álvaro, Isidoro, Gomariz, Rosa P., Juarranz, Yasmina
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126260/
https://ncbi.nlm.nih.gov/pubmed/26818776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12777
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