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Critical Roles of Kupffer Cells in the Pathogenesis of Alcoholic Liver Disease: From Basic Science to Clinical Trials

Alcoholic liver disease (ALD) encompasses a spectrum of liver injury ranging from steatosis to steatohepatitis, fibrosis, and finally cirrhosis. Accumulating evidences have demonstrated that Kupffer cells (KCs) play critical roles in the pathogenesis of both chronic and acute ALD. It has become clea...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Zeng, Tao, Zhang, Cui-Li, Xiao, Mo, Yang, Rui, Xie, Ke-Qin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126119/
https://ncbi.nlm.nih.gov/pubmed/27965666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00538
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