Targeted Next Generation Sequencing of CIC-DUX4 Soft Tissue Sarcomas Demonstrates Low Mutational Burden and Recurrent Chromosome 1p Loss

Gene fusions between CIC and DUX4 define a rare class of soft tissue sarcomas poorly understood at the molecular level. Previous karyotyping and fluorescence in situ hybridization studies support trisomy chromosome 8 as a recurrent alteration, however other driving alterations are largely unknown. T...

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Publicado no:Hum Pathol
Main Authors: de la Vega, Lorena Lazo, Hovelson, Daniel H., Cani, Andi K., Liu, Chia-Jen, McHugh, Jonathan B., Lucas, David R., Thomas, Dafydd G., Patel, Rajiv M., Tomlins, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125884/
https://ncbi.nlm.nih.gov/pubmed/27664537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2016.09.004
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